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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4473 | Ibiglustat | Venglustat,SAR402671,GZ402671 | Transferase |
Ibiglustat (GZ402671) is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor. Ibiglustat blocks the formation of glucosylceramide (GL-1), a key intermediate in the synthe... | |||
T12038 | Migalastat hydrochloride | GR181413A hydrochloride,Migalastat HCl,GR181413A HCl | Others |
Migalastat hydrochloride (GR181413A) is an orally available, potent and competitive inhibitor of alpha-galactosidase A. It promotes the transport of alpha-galactosidase A to the lysosome and can be used in the study of F... | |||
T37192 | 4-Methylumbelliferyl-α-D-Galactopyranoside | 4MU-α-Gal | Others |
4-Methylumbelliferyl-α-D-Galactopyranoside (4MU-α-Gal) (4-MU-α-Gal) is a fluorogenic substrate of α-galactosidase. In addition to its use in characterizing novel α-galactosidases, 4-MU-α-Gal is used in assays to evaluate... | |||
T32923 | Lucerastat | NBDGJ | |
Lucerastat is a very effective and selective α-gal A (α-D-galactosidase) inhibitor for the treatment of lipid storage diseases and Fabry disease. | |||
T39105 | Ibiglustat succinate | GZ402671succinate,Venglustat succinate,Ibiglustat succinate,SAR402671succinate | |
Ibiglustat (Venglustat) succinate is an orally active, brain-penetrant inhibitor of glucosylceramide synthase (GCS). It is utilized in the investigation of Gaucher disease type 3, Parkinson's disease associated with GBA ... | |||
T37438 | C17 Globotriaosylceramide (d18:1/17:0) | C17 Globotriaosylceramide (d18:1/17:0) | |
C17 Globotriaosylceramide is a sphingolipid that has been used as an internal standard for the quantification of globotriaosylceramides in plasma and urine from patients with Fabry disease by GC-MS. | |||
T37291 | Lyso-Globotriaosylceramide (d18:1) | Lyso-Globotriaosylceramide (d18:1) | |
Lyso-globotriaosylceramide is a form of globotriaosylceramide that is lacking the fatty acyl group. It binds to Shiga toxin 1 (Stx1) in the presence of cholesterol and phosphatidylcholine but does not bind Stx2. It also ... | |||
T37439 | C18 Globotriaosylceramide (d18:1/18:0) | ||
C18 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from lactosylceramide . It inhibits aggregation of human neutrophils induced by phorbol 12-myristate 13-acetat... | |||
T37440 | C2 Adamantanyl Galactosylceramide (d18:1/2:0) | ||
C2 Adamantanyl Galactosylceramide (d18:1/2:0) (AdaGalCer) is a bioactive sphingolipid. It reduces globotriaosylceramide 3 synthesis from exogenous lactosylceramide in microsomes. AdaGalCer stimulates recombinant glucocer... | |||
T36859 | C16 Globotriaosylceramide (d18:1/16:0) | C16 Globotriaosylceramide (d18:1/16:0) | |
C16 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from C16 lactosylceramide . C16 globotriaosylceramide acts as a receptor for Shiga toxin in B cell-derived Raj... | |||
T36185 | Globotriaosylceramides (hydroxy) (porcine) | ||
Globotriaosycleramides are glycosphingolipids found in mammalian cell membranes that are synthesized from lactosylceramides . They act as receptors for Shiga and Shiga-like toxins in vitro and in vivo. Globotriaosylceram... | |||
T36186 | Globotriaosylceramides (porcine) | ||
Globotriaosycleramides are glycosphingolipids found in mammalian cell membranes that are synthesized from lactosylceramides . They act as receptors for Shiga and Shiga-like toxins in vitro and in vivo. Globotriaosylceram... |